Alabama rot, also known as CRGV (cutaneous and renal glomerular vasculopathy) is a very rare, potentially life-threatening disease in dogs, causing damage to the blood vessels in the skin and sometimes the kidney. Tiny blood clots form in the blood vessels which blocks them, and in the skin it causes ulceration, but in the kidney, it can lead to severe organ dysfunction (kidney failure).
Some dogs develop skin sores only, whilst others develop skin sores and kidney failure. Recovery is expected in the former group; however, sadly many dogs that develop kidney failure do not survive because of this disease.